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Aciclovir has a high distribution rate; protein binding is reported to range from 9 to 33%.Since discovery in mid 1970s, it is being used as an effective drug for the treatment of infections caused by most known species of the Herpes virus family including Herpes zoster & Varicella zoster viruses.Lebensbaum (occidentalis "Brabant" oder "Smaragd") , Kirschlorbeer (Prunus "Herbergii", "Novita" oder "Etna").Zu dieser Kategorie zählen auch unsere fertigen Heckenelemente, mit denen Sie einen schnellen bzw. alternativ für eine künstliche Sichtschutzwand) für Ihren Garten errichten können.This finding emphasizes the importance of testing simple, inexpensive non-ART strategies, such as aciclovir and cotrimoxazole, in people with HIV.Aciclovir is excreted in the breast milk, therefore it is recommended that caution should be used in breast-feeding women.
Varicella zoster virus-produced plaques in monolayers of MRC5 cells.
Aciclovir crystalline nephropathy is more common when aciclovir is given as a rapid infusion and in patients with dehydration and preexisting renal impairment.
Adequate hydration, a slower rate of infusion, and dosing based on renal function may reduce this risk.
Richard Whitley, a University of Alabama at Birmingham researcher and pioneer in antiviral therapy, was the first to successfully use the drug in humans.
Aciclovir is the INN and BAN while acyclovir is the USAN and former BAN.
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It was originally marketed as Zovirax; patents expired in the 1990s and since then it is generic and is marketed under many brand names worldwide.